Agent-Native Immune System: Architecture, Taxonomy, and Engineering
Evolving story · 2 updatesAI Agent Security FrameworkTimeline →Researchers propose an Agent-Native Immune System (ANIS) to address runtime security vulnerabilities in autonomous AI agents, highlighting flaws in current defense mechanisms like perimeter security and alignment.
The transition from static chat bots to autonomous agents--equipped with persistent memory, tool-use protocols, and multi-agent collaboration--has fundamentally expanded the AI threat landscape. Current defense mechanisms, such as perimeter security and training-time alignment, remain external to the agent's active reasoning loop. Consequently, they fall short: a fully aligned agent remains highly vulnerable to runtime hijacking via memory poisoning, tool-chain manipulation, or multi-agent protocol attacks. To address this critical gap, we introduce the Agent-Native Immune System (ANIS), the f
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